Published: 2017-04-25

To assess the effects of platelet rich plasma application on pain in osteoarthritis knee

Rahul Kadam, Ankit Agrawal, Abhay Chhallani, Santosh Pandhare, Abhishek Gupta, Ritesh Sawant


Background: Platelet rich plasma (PRP) is a concentrate extract of platelets from autologous blood. It is known to increase growth factor of plasma and helps to heal the injured tissue. Platelet-rich plasma (PRP) is an autologous biologic treatment including patients own plasma, containing growth factors released from platelets. The rationale for the use of PRP is to stimulate the natural healing cascade and tissue regeneration by an increase release of platelet-derived factors directly at the site of treatment. This study is done to assess the effects of platelet rich plasma application on pain in osteoarthritis knee.

Methods: Total of 40 cases was included in this study (18 male and 22 females) with mean age of 57.3 (Range 35-75). All patients received intra-articular PRP injection. This study was conducted on the patients coming to orthopaedic department at MGM medical college and hospital, Navi Mumbai.

Results: In this study it was found that there is decrease in pain on vas pain score, with increasing time. We followed up the patients for period of 3 months. We found that average mean VAS score was decreased from 6.0 to 4.13 after follow up of 3 months after a single dose of intra-articular PRP injection.

Conclusions: PRP is an effective treatment for pain in OA knee. It is one of the new approaches in the field of orthopaedics to solve the issues of pain management.


PRP, Osteoarthritis knee, Intra-articular injection

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