The incidence of symptomatic deep vein thrombosis and pulmonary embolism, following THA in patients, with postoperative chemoprophylaxis in Indian population
DOI:
https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20184711Keywords:
Deep vein thrombosis, Pulmonary embolism, Prophylaxis, Total hip arthroplasties, Venous thromboembolismAbstract
Background: Deep vein thrombosis (DVT) and pulmonary embolism (PE) can occur in patients after elective total hip arthroplasties (THA). Indian population appears to have low incidence of DVT and PE in comparison with Western population due to difference in ethnicity, genetic make-up, social life styles. The study intends to find the incidence of symptomatic DVT and PE in postoperative THA patients. The aim of the study was to study the incidence of symptomatic DVT and PE, in post-THA patients in Indian Population.
Methods: Retrospective study conducted from 1st January, 2017 to 31st July, 2018 in BIRRD (T) Hospital. All patients who underwent THA are included, after fulfilling inclusion and exclusion criteria. Patients were evaluated for symptoms during the hospital stay and after discharge for 3 Months.
Results: Total number of patients who had THA were 447 (n=447). The symptomatic DVT was found in 1 (n=1) patient. He developed DVT (n=1) during the study period, in first 48 hours postoperatively and recovered with ICU management. The same patient showed symptoms of PE but recovered fully. All patients were on a prophylactic regimen.
Conclusions: Our results suggest incidence of DVT and PE are low in the Indian population with a prophylactic regimen.
References
No authors enlisted. Prevention of venous thrombosis and pulmonary embolism. NIH Consensus Development. JAMA. 1986;6(2):1-8.
Lee SY, Ro DH, Chung CY, Lee KM, Kwon SS, Sung KH, et al. Incidence of DVT after major lower limb orthopedic surgery: Analysis of nationwide chain Registry. Yonsei Med J. 2015;56(1):139–45.
Nachiketan Dore K, Gopi M, Sathish Devadoss, Devadoss A. Incidence of post-operative deep vein thrombosis in patients undergoing joint replacement surgeries of lower limb. Int J Orthop Sci. 2017;3(3):140-4.
Kamerkar DR, Joseph J, Desai SC, Dsilva LC, Joglekar SJ. Arrive: A retrospective registry of Indian patients with venous thromboembolism. Indian J Crit Care Med. 2016;20(3):150–8.
Pal CP, Singh P, Chaturvedi S, Pruthi KK, Vij A. Epidemiology of knee osteoarthritis in India and related factors. Indian J Orthop. 2016;50(5):518–22.
Junapudi SS, Rao BB. A comparative study of cardiovascular disease risk factors among urban and rural population South Indian city. Int J Community Med Public Health. 2017;4(12):4623-5.
Mukhopadhaya B, Barooah B. Osteoarthritis of hip in Indians. An anatomical and clinical study. Ind J Orthop. 1967;1:55-62.
Chauhan R, Paul S, Dhaon BK. Primary osteoarthritis of hip joint in Indians A cadaveric study. Indian J Orthop. 2002;36:7.
Losina E, Weinstein AM, Reichmann WM, Burbine SA, Solomon DH, Daigle ME, et al. Lifetime risk and age of diagnosis of symptomatic knee osteoarthritis in the US. Arthritis Care Res (Hoboken). 2013;65(5):10.
Jain V, Dhaon BK, Jaiswal A, Nigam V, Singla J. Deep vein thrombosis after total hip and knee arthroplasty in Indian patients. Postgrad Med J. 2004;80:729–31.
Pachore JA, Vaidya SV, Thakkar CV, Bhalodia HKP, Wakankar HM. ISHKS joint registry:A preliminary report. Indian J Orthop. 2013;47(5):505–9.
Kim YH, Oh SH, Kim JS. Incidence And Natural History Of Deep-Vein Thrombosis After Total Hip Arthroplasty. J Bone Joint Surg [Br]. 2003;85:661-5.
Bagaria V, Modi N, Panghate A, Vaidya S. Incidence and risk factors for development of venous thromboembolism in Indian patients undergoing major orthopedic surgery: Results of a prospective study. Postgrad Med J. 2006;82:136–9.
Agarwala S, Bhagwat AS, Modhe J. Deep vein thrombosis in Indian patients undergoing major lower limb surgery. Indian J Surg. 2003;65:159–62.
Sun Y, Chen D, Xu Z, Shi D, Dai J, Qin J, et al. Incidence of Symptomatic and Asymptomatic Venous Thromboembolism After Elective Knee Arthroscopic Surgery: A Retrospective Study With Routinely Applied Venography. Arthroscopy. 2014;30(7):818-22.
Quinlan QJ, Eikelboom JW, Dahl OE, Eriksson BI, Sidhu PS, Hirsh J. Association between asymptomatic deep vein thrombosis detected by venography and symptomatic venous thromboembolism in patients undergoing elective hip or knee surgery. J Thrombosis Haemostasis. 2007;5:1438–43.
Ajay Kakkar K, Sophie K, Smith R. Incidence of venous thromboembolism in orthopedic surgeries. London: Springer-Verlag; 2013.
Januel JM, Chen G, Ruffieux C, Quan H, Douketis JD, Mark A, et al. Symptomatic In-Hospital Deep Vein Thrombosis and Pulmonary Embolism Following Hip and Knee Arthroplasty Among Patients Receiving Recommended Prophylaxis. JAMA. 2012;307(3):294-303.
Dhillon KS, Askander A, Doraisamy S. Postoperative deep vein thrombosis in Asian patients is not a rarity. J Bone Joint Surg. (Br).1996;78:427–30.
Piovella F, Wang CJ, Lu H, Lee K, Lee LH, Lee WC, et al. Deep-vein thrombosis rates after major orthopedic surgery in Asia. An epidemiological study based on postoperative screening with centrally adjudicated bilateral venography. J Thromb Haemost. 2005;3(12):2664-70.
O’Reilly RF, Burgess IA, Zicat B. The prevalence of venous thromboembolism after hip and knee replacement surgery. MJA. 2005;182:154–9.
