Functional outcome of wide resection and autologous avascular proximal fibular graft arthroplasty in distal radius GCT

Authors

  • Yuvaraja Murugan Department of Orthopedics, Pondicherry Institute of Medical Sciences, Puducherry, India
  • Balasubramaniam Shanmugasundaram Institute of Orthopedics and Traumatology, Madras Medical College, Chennai, Tamil Nadu, India
  • Kamalasekaran Dulasi Department of Orthopedics, Government Hospital, Thirukovilur, Tamil Nadu, India
  • Singaravadivelu Vaidyanathan Institute of Orthopedics and Traumatology, Madras Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20185143

Keywords:

Distal radius GCT, Autologous fibular arthroplasty, Wide resection

Abstract

Background: Giant cell tumor (GCT) of distal radius usually presents in late stages with aggressive progression. Extended curettage alone is usually inadequate and wide resection is the most common surgery performed. Reconstruction of the resulting defect poses significant challenges.

Methods: 11 patients with distal radius GCT treated with wide resection and autologous avascular proximal fibular graft arthroplasty were studied retrospectively. One patient was Campanacci grade II and the rest 10 were Campanacci grade III. All patients underwent a standard preoperative workup and underwent a standard procedure. Patients were followed up for a mean period of 33 months (range: 1 year–7 years). Wrist movements were documented and functional outcome was scored using revised musculoskeletal tumor society scoring (MSTS).

Results: Of the 11 patients, eight had excellent outcome, two had good outcome and one had satisfactory outcome according to MSTS scoring. Mean dorsiflexion, palmar flexion, supination and pronation was 44 degrees (range 10-80), 34 degrees (range 10-70), 60 degrees (range 20-80), 54 degrees (range 15-70) respectively. The complications encountered were fibulo-ulnar diastasis in 3 patients, fibulo-carpal subluxation in 2 patients, soft tissue recurrence in 1 patient and graft site non-union in 1 patient. Despite fibula-ulnar and fibula-carpal instability functional outcomes were seen to be excellent (4 patients) or good (1 patient).

Conclusions: Avascular autologous proximal fibular arthroplasty provides for excellent to good functional outcomes after wide resection in distal radius GCT even if radiological appearances are suboptimal.

Metrics

Metrics Loading ...

References

Unni KK, Inwards CY. Dahlin’s Bone Tumors: General Aspects and Data on 10,165 Cases. Philadelphia, PA: Lippincott Williams & Wilkins, 6th ed. 2010: 225-242.

Szendroi M. Giant-cell tumor of bone. J Bone Joint Surg Br 2004;86(1):5-12.

Sung HW, Kuo DP, Shu WP, Chai YB, Liu CC, Li SM. Giant-cell tumor of bone:analysis of two hundred and eight cases in Chinese patients. J Bone Joint Surg Am. 1982;64(5):755-61.

O’Donnell RJ, Springfield DS, Motwani HK, Ready JE, Gebhardt MC, Mankin HJ. Recurrence of giant-cell tumors of the long bones after curettage and packing with cement. J Bone Joint Surg Am. 1994;76(12):1827-33.

Cheng JC, Johnston JO. Giant-cell tumor of bone: prognosis and treatment of pulmonary metastases. Clin Orthop. 1997;338(1):205-14.

Tubbs WS, Brown LR, Beabout JW, Rock MG, Unni KK. Benign giant-cell tumor of bone with pulmonary metastases: clinical findings and radiological appearance of metastases of 13 cases. AJR Am J Roentgenol. 1992;158(2):331-4.

Blackley HR, Wunder JS, Davis AM, et al. Treatment of giant-cell tumors of long bones with curettage and bone-grafting. J Bone Joint Surg [Am]. 1999;81(6):811-20.

Athanasian EA, Wold LE, Amadio PC. Giant-cell tumors of the bones of the hand. J Hand Surg Am 1997;22(1):91-8.

Cheng CY, Shih HN, Hsu KY, Hsu RWW. Treatment of giant cell tumour of the distal radius. Clin Orthop. 2001;383(1):221-8.

Szendröi M. Giant-cell tumor in the radius: aggressiveness and soft-tissue recurrence. Chir Organi Mov. 1990;(75):241-3.

McDonald DJ, Sim FH, McLeod RA, Dahlin DC. Giant-cell tumor of bone. J Bone Joint Surg Am. 1986;68(2):235-42.

Chadha M, Arora SS, Singh AP, Gulati D, Singh AP. Autogenous nonvascularized fibula for treatment of giant cell tumor of distal end radius. Arch Orthop Trauma Surg. 2010;130(12):1467-73.

Cheng CY, Shih HN, Hsu KY, Hsu RW:Treatment of giant cell tumor of the distal radius. Clin Orthop Relat Res. 2001;383(1):221-8.

Campanacci M, Giunti A, Olmi R. Giant-cell tumours of bone: a study of 209 cases with long term follow up in 130. Ital J Orthop Traumatol. 1975;1(2):249-77.

Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res. 1993;286(1):241-6.

Johnson EW Jr, Dahlin DC. Treatment of giant-cell tumor of bone. J Bone Joint Surg Am. 1959;41(5):895-904.

Campanacci M, Baldini N, Bariani S, Sudanese A. Giant-cell tumor of bone. J Bone Joint Surg [Am]. 1987;69(1):106-14.

Antal I, Sápi Z, Szendröi M. The prognostic significance of DNA cytophotometry and proliferation index (Ki-67) in giant cell tumors of bone. Int Orthop. 1999;23(6):315-9.

Lausten GS, Jensen PK, Schiodt T, Lund B. Local recurrences in giant cell tumour of bone:long-term follow up of 31 cases. Int Orthop. 1996;20(3):172-6.

Masui F, Ushigome S, Fujii K. Giant cell tumor of bone: a clinicopathologic study of prognostic factors. Pathol Int. 1998;48(9):723-9.

Schajowicz F. Tumors and tumorlike lesions of bone and joints. New York: Springer-Verlag; 1981: 220-228.

Sanerkin NG. Malignancy, aggressiveness, and recurrence in giant cell tumor of bone. Cancer. 1980;46(7):1641-9.

Bridge JA, Mouron BJ, Neff JR, Bhatia PS. Significance of chromosomal abnormalities in a malignant giant cell tumor of bone. Cancer Genet Cytogenet. 1991;57(1):87-92.

Bridge JA, Neff JR, Bhatia PS, Sanger WG, Murphey MD. Cytogenetic findings and biologic behaviour of giant cell tumors of bone. Cancer. 1990;65(12):2697-703.

Schoedel KE, Greco MA, Stetler-Stevenson WG, Ohori NP, Goswami S, Present D, et al. Expression of metalloproteinases and tissue inhibitors of metalloproteinases in giant cell tumor of bone: an immunohistochemical study with clinical correlation. Hum Pathol. 1996;27(11):1144-8.

Peimer CA, Schiller AL, Mankin HJ, Smith RJ. Multicentric giant cell tumor of bone. J Bone Joint Surg [Am]. 1980;62(4):652-6.

Masui F, Ushigome S, Fujii K. Giant cell tumor of bone: an immunohistochemical comparative study. Pathol Int. 1998;48(5):355-61.

Gitelis S, Mallin AB, Piasecki P, Turner F. Intralesional excision compared with en bloc resection for giant-cell tumors of bone. J Bone Joint Surg [Am]. 1993;75(11):1648-55.

Kumita SM, Leong PC, Yip K, Hung LK, Panozzo A, Kew J. Vascularized bone grafts in the treatment of juxta-articular giant-cell tumors of the bone. J Reconst Microsurg. 1998;14(3):185-90.

Labs K, Perka C, Schmidt GR. Treatment of stages 2 and 3 giant-cell tumor. Arch Orthop Traum Surg. 2001;121(1-2):83-6.

Vander Griend RA, Funderburk CH. The treatment of giant-cell tumors of the distal part of the radius. J Bone Joint Surg Am. 1993;75(6):899-908.

Pho RW. Free vascularised fibular transplant for replacement of the lower radius. J Bone Joint Surg Br. 1979;61(3):362-5.

Pho RW. Malignant giant-cell tumor of the distal end of the radius treated by a free vascularized fibular transplant. J Bone Joint Surg Am. 1981;63(6):877-84.

Hsu RW, Wood MB, Sim FH, Chao EY. Free vascularised fibular grafting for reconstruction after tumour resection. J Bone Joint Surg Br. 1997;79(1):36-42.

Puri A, Gulia A, Agarwal MG, Reddy K. Ulnar translocation after excision of a Campanacci grade-3 giant-cell tumour of the distal radius: an effective method of reconstruction. J Bone Joint Surg Br. 2010;92(6):875-9.

Kocher MS, Gebhardt MC, Mankin HJ. Reconstruction of the distal aspect of the radius with use of an osteoarticular allograft after excision of a skeletal tumor. J Bone Joint Surg Am. 1998;80(3):407-19.

Szabo RM, Anderson KA, Chen JL. Functional outcome of en bloc excision and osteoarticular allograft replacement with the Sauve-Kapandji procedure for Campanacci grade 3 giant-cell tumor of the distal radius. J Hand Surg Am. 2006;31(8):1340-8.

Bianchi G, Donati D, Staals EL, Mercuri M. Osteoarticular allograft reconstruction of the distal radius after bone tumour resection. J Hand Surg Br. 2005;30(4):369-73.

Gold AM. Use of a prosthesis for the distal portion of the radius following resection of a recurrent giant-cell tumor. J Bone Joint Surg Am. 1965;47(1):216-8.

Gold AM. Use of a prosthesis for the distal portion of the radius following resection of a recurrent giant-cell tumor. J Bone Joint Surg Am. 1957;39(6):1374-80.

Hatano H, Morita T, Kobayashi H, Otsuka H:A ceramic prosthesis for the treatment of tumours of the distal radius. J Bone Joint Surg Br. 2006;88(12):1656-8.

Downloads

Published

2018-12-25

How to Cite

Murugan, Y., Shanmugasundaram, B., Dulasi, K., & Vaidyanathan, S. (2018). Functional outcome of wide resection and autologous avascular proximal fibular graft arthroplasty in distal radius GCT. International Journal of Research in Orthopaedics, 5(1), 42–49. https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20185143

Issue

Section

Original Research Articles