Limb salvage with wide resection and endoprosthetic reconstruction for giant cell tumour of proximal tibia: a case report
DOI:
https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20262932Keywords:
Giant cell tumour, Proximal tibia, Limb salvage surgery, Endoprosthesis, Knee reconstructionAbstract
Giant Cell Tumour of Bone (GCT)is a locally aggressive benign bone tumour commonly affecting the epiphyseal region of long bones in skeletally mature individuals. The proximal tibia is among the most frequently involved sites. Surgical management becomes challenging when the tumour extends into surrounding soft tissues and requires wide excision with reconstruction. A4I-year-old female presented with pain, swelling around the left knee joint, and difficulty in weight bearing for three months without a history of trauma. Clinical examination revealed swelling over the proximal tibia, tenderness, and painful restriction of terminal knee movements. Radiographs demonstrated a lytic lesion involving the proximal tibia, and MRI revealed a giant cell tumour with posterior extension. The patient underwent wide resection of the proximal tibia with limb salvage reconstruction using a proximal tibial endoprosthesis. Histopathological examination confirmed the diagnosis of giant cell tumour. Postoperative recovery was uneventful. Limb salvage with endoprosthetic reconstruction provided stable knee joint function and adequate oncological clearance. Wide excision with endoprosthetic reconstruction is an effective treatment option for giant cell tumours of the proximal tibia with extraosseous extension, providing both tumour control and functional limb preservation.
References
Roy M, Reddy HV, Bhikshavarthimath SA, Dwidmuthe SC, Tiwari V. Rare coexistence: Giant cell tumor recurrence and infection in the proximal tibia – A case report. J Orthop Case Rep. 2025;15(1):26-30.
Harishkumar M, Choudhary BM, Ganesh A, Lourdes K. Advanced surgical management of proximal tibia giant cell tumor using extended curettage and sandwich technique: A case report. J Orthop Case Rep. 2025;15(8):158-63.
Gupta VA, Tomar A, Katkani A, Modi L, Desai SM. Modular custom prosthetic reconstruction of proximal tibia giant cell tumor: A case report and review of the literature. Int J Res Orthop. 2025;11(3):635-8.
Roy A, Vadakke Puthiyottil SS, Edayattil A. Denosumab in giant cell tumour of bone: A case series with review of literature. Asian Pac J Cancer Care. 2026;11(2):293-301.
Govindaraj V, Chellamuthu S, Vemuri MB, Rajesh NG. Giant-cell tumor of dorsal vertebra presenting as a posterior mediastinal mass: A rare case report. Indian J Chest Dis Allied Sci. 2024;66(2):64-7.
Gundavda MK, Agarwal MG. Extended curettage for giant cell tumors of bone: A surgeon's perspective. JBJS Essent Surg Tech. 2021;11(1):e20.00040.
Meena AM, Jain P, Dayma RL. Retrospective study of function outcome in giant cell tumor treated by sandwich technique with internal fixation. Int J Orthop Sci. 2017;3(2):817-22.
Moaiyadi AH, Wankhede AK, Badole CM, Patond KR. Case of giant cell tumour of proximal tibia treated with intra-lesion curettage with adjuvant therapy and reconstruction with the sandwich technique fixation. Int J Res Orthop. 2023;9(1):213-6.
Chawla S, Mehta S, Agarwal R. Management of giant cell tumor around the knee: A retrospective analysis from an Indian tertiary care centre. Indian J Orthop. 2021;55(5):1204-11.
Sharma V, Batra S, Kapoor SK. Surgical management of giant cell tumor around the knee joint: Functional outcomes and recurrence rate. J Clin Orthop Trauma. 2020;11(4):674-8.
Natarajan MV, Kumar R, Rajkumar N. Limb salvage surgery for bone tumors using custom mega prosthesis: Experience from an Indian center. Indian J Orthop. 2020;54(3):311-8.
Agarwal MG, Gundavda MK. Current concepts in the management of giant cell tumor of bone. Indian J Orthop. 2022;56(2):167-75.
Sharma S, Maheshwari AV, Jain VK. Surgical treatment and recurrence pattern of giant cell tumor around the knee. J Orthop Surg (Hong Kong). 2021;29(3):1-7.
Singh S, Kumar D, Tiwari A. Giant cell tumor of proximal tibia treated with curettage and bone cement: A case report. Int J Orthop Sci. 2020;6(3):345-8.
Patel A, Shah K, Desai N. Management of giant cell tumor of bone with extended curettage and bone cement: Experience from a tertiary hospital in India. Cureus. 2023;15(5):e42132.