Ortho-biological management of osteonecrosis in sickle cell disease using core decompression with platelet-rich plasma: a case report

Authors

  • Vijay A. Kulkarni Department of Orthopaedics, KIMS Hospital, Electronic City, Bangalore, Karnataka, India
  • Abhijith Bapuram Department of Orthopaedics, KIMS Hospital, Electronic City, Bangalore, Karnataka, India
  • Mohan Kumar Jagadeesan Department of Orthopaedics, KIMS Hospital, Electronic City, Bangalore, Karnataka, India
  • Santosh Kumar Hakkalamani Department of Orthopaedics, KIMS Hospital, Electronic City, Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20261238

Keywords:

Avascular necrosis, Sickle cell disease, Ficat-Aarlet, Core decompression, Platelet rich plasma

Abstract

Avascular necrosis (AVN) is a debilitating manifestation of sickle cell disease (SCD) caused due to structural abnormality of the red blood cells and the precarious blood supply of the femoral head. Prompt identification of the condition in susceptible individuals is of utmost importance. Here, we present a case of SCD with bilateral AVN in Ficat-Arlet stages IIb (left hip) and I (right hip) which was managed by core decompression augmented with platelet rich plasma.

References

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Aggarwal AK, Poornalingam K, Jain A, Prakash M. Com bining platelet-rich plasma instillation with core decompres sion improves functional outcome and delays progression in early-stage avascular necrosis of femoral head: A 4.5- to 6-year prospective randomized comparative study. J Arth Roplasty. 2021;36(1):54-61.

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Published

2026-04-27

How to Cite

Kulkarni, V. A., Bapuram, A., Jagadeesan, M. K., & Hakkalamani, S. K. (2026). Ortho-biological management of osteonecrosis in sickle cell disease using core decompression with platelet-rich plasma: a case report. International Journal of Research in Orthopaedics, 12(3), 818–820. https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20261238

Issue

Vol. 12 No. 3 (2026): May-June 2026

Section

Case Reports
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