Is motion the best medicine? Rethinking knee osteoarthritis through gait analysis

Authors

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20260532

Keywords:

Motion, Rethinking knee osteoarthritis , Gait analysis

Abstract

A gradual degenerative joint disease, knee osteoarthritis (OA), places an enormous strain on healthcare systems around the world, especially in older people and those with metabolic and biomechanical risk factors. Knee OA causes crippling pain, stiffness, and functional incapacity. It is characterized by the slow deterioration of articular cartilage, subchondral bone sclerosis, osteophyte formation, and persistent synovial inflammation. Because of its intricate pathophysiology and the interaction between systemic inflammation and biomechanical stressors, the disease continues to pose a significant challenge, even with the availability of pharmacologic medicines, intra-articular therapy, and surgical procedures.

Metrics

Metrics Loading ...

References

Reichenbach S, Felson DT, Hincapié CA, Heldner S, Bütikofer L, Lenz A, et al. Effect of biomechanical footwear on knee pain in people with knee osteoarthritis: the BIOTOK randomized clinical trial. JAMA. 2020;323(18):1802-12. DOI: https://doi.org/10.1001/jama.2020.3565

Timmins KA, Leech RD, Batt ME, Edwards KL. Running and knee osteoarthritis: a systematic review and meta-analysis. Am J Sports Med. 2017;45(6):1447-57. DOI: https://doi.org/10.1177/0363546516657531

Marcum ZA, Zhan HL, Perera S, Moore CG, Fitzgerald GK, Weiner DK. Correlates of gait speed in advanced knee osteoarthritis. Pain Med. 2014;15(8):1334-42. DOI: https://doi.org/10.1111/pme.12478

Woolacott NF, Corbett MS, Rice SJ. The use and reporting of WOMAC in assessing the benefit of physical therapies for knee osteoarthritis pain: findings from a systematic review of clinical trials. Rheumatology. 2012;51(8):1440-6. DOI: https://doi.org/10.1093/rheumatology/kes043

Sharma L, Song J, Felson DT, Cahue S, Shamiyeh E, Dunlop DD. The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA. 2001;286(2):188-95. DOI: https://doi.org/10.1001/jama.286.2.188

Hutchison L, Grayson J, Hiller C, D'Souza N, Kobayashi S, Simic M. Relationship between knee biomechanics and pain in people with knee osteoarthritis: a systematic review and meta‐analysis. Arthritis Care Res. 2023;75(6):1351-61. DOI: https://doi.org/10.1002/acr.25001

Tas S, Guneri S, Kaymak B, Erden Z. A comparison of results of 3-dimensional gait analysis and observational gait analysis in patients with knee osteoarthritis. Acta Orthop Traumatol Turc. 2015;49(2):151-9. DOI: https://doi.org/10.3944/AOTT.2015.14.0158

Kaufman KR, Hughes C, Morrey BF, Morrey M, An KN. Gait characteristic of patients with knee osteoarthritis. J Biomechan. 2001;34(7):907-15. DOI: https://doi.org/10.1016/S0021-9290(01)00036-7

Naili JE, Esbjörnsson AC, Iversen MD, Schwartz MH, Hedström M, Häger CK, et al. The impact of symptomatic knee osteoarthritis on overall gait pattern deviations and its association with performance-based measures and patient-reported outcomes. The Knee. 2017;24(3):536-46.

Naili JE, Esbjörnsson AC, Iversen MD, Schwartz MH, Hedström M, Häger CK, et al. The impact of symptomatic knee osteoarthritis on overall gait pattern deviations and its association with performance-based measures and patient-reported outcomes. The Knee. 2017;24(3):536-46. DOI: https://doi.org/10.1016/j.knee.2017.02.006

Favre J, Jolles BM. Gait analysis of patients with knee osteoarthritis highlights a pathological mechanical pathway and provides a basis for therapeutic interventions. EFORT open Rev. 2016;1(10):368-74. DOI: https://doi.org/10.1302/2058-5241.1.000051

Ornetti P, Maillefert JF, Laroche D, Morisset C, Dougados M, Gossec L. Gait analysis as a quantifiable outcome measure in hip or knee osteoarthritis: a systematic review. Joint Bone Spine. 2010;77(5):421-5. DOI: https://doi.org/10.1016/j.jbspin.2009.12.009

Mills K, Hunt MA, Ferber R. Biomechanical deviations during level walking associated with knee osteoarthritis: a systematic review and meta‐analysis. Arthritis Care Res. 2013;65(10):1643-65. DOI: https://doi.org/10.1002/acr.22015

Levinger P, Menz HB, Fotoohabadi MR, Feller JA, Bartlett JR, Bergman NR. Foot posture in people with medial compartment knee osteoarthritis. J Foot Ankle Res. 2010;3:1-8. DOI: https://doi.org/10.1186/1757-1146-3-29

Downloads

Published

2026-02-24

How to Cite

Rastogi, A., Kalia, R. B., & Meena, P. K. (2026). Is motion the best medicine? Rethinking knee osteoarthritis through gait analysis. International Journal of Research in Orthopaedics, 12(2), 543–544. https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20260532