Comparative analysis of landmark-guided intra-articular knee injections in outpatient clinics versus ultrasound-guided injections: a quality improvement study

Authors

  • Sangeetha Baskar Department of Trauma and Orthopaedics, Lewisham and Greenwich NHS Trust, London, United Kingdom
  • Saphalya Pattnaik Department of Trauma and Orthopaedics, Lewisham and Greenwich NHS Trust, London, United Kingdom
  • Mohamed Khalid Department of Trauma and Orthopaedics, Lewisham and Greenwich NHS Trust, London, United Kingdom
  • Sagaya J. Leo Department of Trauma and Orthopaedics, Lewisham and Greenwich NHS Trust, London, United Kingdom
  • Gur A. Sidhu Department of Trauma and Orthopaedics, Kings College Hospital NHS Foundation Trust, London, United Kingdom
  • Mothana Gawad Department of Trauma and Orthopaedics, Guy’s and St Thomas’s NHS Foundation Trust, London, United Kingdom

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20254201

Keywords:

Osteoarthritis, Knee injections, Ultrasound-guided, Landmark-guided, Cost-effectiveness

Abstract

Background: Osteoarthritis (OA) of the knee is a prevalent cause of chronic pain and reduced mobility. Intra-articular steroid injections are a key management option when oral analgesics fail to improve symptoms and surgery is not imminent. These injections can be performed using ultrasound guidance or anatomical landmark techniques (“blind”) depending on clinician expertise and hospital setting. However, referring patients for ultrasound (US) -guided procedures may increase waiting times and costs imposing a significant burden on hospital resources.

Methods: A closed-loop audit at a London district general hospital evaluated the clinical and economic impact of US-guided versus landmark-guided intra-articular knee injections for osteoarthritis in an outpatient orthopaedic setting. The first (retrospective) cycle covered January–December 2023, and the second (prospective) cycle May–December 2024. Data from electronic health records, Picture Archiving and Communication Systems (PACS), and National Health Service (NHS) cost databases were analysed for waiting times (weeks) and procedural costs (£).

Results: In 2023, 391 US-guided injections had an average waiting time of 16.2 weeks and cost ~£700 each, while 182 landmark-guided clinic injections averaged 15 weeks and cost ~£600. In 2024, 346 US-guided and 234 landmark-guided injections were performed, reducing US waiting times to nine weeks. A revised costing model achieved annual savings of ~£96,000. Increased clinic-based procedures reduced US demand, with no reported adverse events.

Conclusion: Clinic-based, landmark-guided knee injections provide a safe, cost-effective and efficient alternative to US-guided procedures, significantly reducing waiting times, and preserving radiology resources while improving care delivery without compromising patient outcomes.

References

Castro‐Domínguez F, Vargas‐Negrín F, Pérez C, Gutiérrez‐Prieto H, Rebollo P. Unmet needs in the osteoarthritis chronic moderate to severe pain Management in Spain: a real word data study. Rheumatol Ther. 2021;8:1113-27.

NICE. Management of osteoarthritis. 2022. Available at: https://www.nice.org.uk/guidance/ ng226/resources/visual-summary-on-the-management-of-osteoarthritis-pdf-11251842157. Accessed on 05 May 2025.

Oo WM, Hunter J. Intra‐articular therapies for knee osteoarthritis: current update. Curr Treatm Opt Rheumatol. 2023;9:99-119.

Hollander JL, Brown EM Jr, Jessar RA, Brown CY. Hydrocortisone and cortisone injected into arthritic joints; comparative effects of and use of hydrocortisone as a local antiarthritic agent. J Am Med Assoc. 1951;147(17):1629-35.

Oo WM, Linklater J, Siddiq MAB, Fu K, Hunter DJ. Comparison of ultrasound guidance with landmark guidance for symptomatic benefits in knee, hip and hand osteoarthritis: Systematic review and meta-analysis of randomised controlled trials. Australas J Ultrasound Med. 2024;27(2):97-105.

Oo WM, Liu X, Hunter DJ. Pharmacodynamics, efficacy, safety and administration of intra-articular therapies for knee osteoarthritis. Expert Opin Drug Metab Toxicol. 2019;15(12):1021-32.

Parry E, Ahmed K, Evans S, Guest E, Klaire V, Koodaruth A, et al. GP assessment of unmet need in a complex multimorbid population using a data-driven and clinical triage system: a prospective cohort study. BJGP Open. 2023;7(4):BJGPO.

Gov.UK. Road to recovery: the government's 2025 mandate to NHS England. 2025. Available at: https://www.gov.uk/government/publications/road-to-recovery-the-governments-2025-mandate-to-nhs-england/road-to-recovery-the-governments-2025-mandate-to-nhs-england. Accessed on 05 May 2025.

Li L, Nahas S, Jandoo R, Williams S, Ganippa HPL, Bhattacharya R, et al. The Mass Knee Clinic: a new NHS outpatient care model showing clinically led transformation in practice. BMJ Innovations. 2021;7:117-22.

Denton E, Robinson P. The changing NHS and imaging services: impact on musculoskeletal imaging. AJR Am J Roentgenol. 2010;195(3):561-2.

Kokubun BA, Manista GC, Courtney PM, Kearns SM, Levine BR. Intra-Articular Knee Injections Before Total Knee Arthroplasty: Outcomes and Complication Rates. J Arthroplasty. 2017;32(6):1798-802.

NHS England. NHS Diagnostic Waiting Times and Activity Data. Available at: https://www.england. nhs.uk/statistics/wp-content/uploads/sites/2/ 2025/01/DWTA-November-2024-Report.pdf. Accessed on 05 May 2025.

Cunnington J, Marshall N, Hide G, Bracewell C, Isaacs J, Platt P, Kane D. A randomized, double-blind, controlled study of ultrasound-guided corticosteroid injection into the joint of patients with inflammatory arthritis. Arthritis Rheumatism. 2010;62(7):1862-9.

Jackson DW, Evans NA, Thomas BM. Accuracy of needle placement into the intra-articular space of the knee. J Bone Joint Surg Am. 2002;84(9):1522-7.

Hall S, Buchbinder R. Do imaging methods that guide needle placement improve outcome? Ann Rheum Dis. 2004;63(9):1007-8.

Wilmer L Jr, Band P, Kettwich L, Chavez-Chiang, Natalia R. A Randomized Controlled Trial Evaluating the Cost-Effectiveness of Sonographic Guidance for Intra-Articular Injection of the Osteoarthritic Knee. J Clin Rheumatol. 2011;17(8):409-15.

NHS England. NHS Diagnostic Waiting Times and Activity Data. Available at: https://www.england. nhs.uk/statistics/wp-content/uploads/sites/2/2025/01 /DWTA-November-2024-Report.pdf. Accessed on 05 May 2025.

NHS England. Financial performance update. Referral to treatment. Available at: https://www. england.nhs.uk/rtt/. Accessed on 05 May 2025.

NHS England. Financial performance update. Available at: https://www.england.nhs.uk/long-read/financial-performance-update-5/#:~:text=For% 202024%2F25%20NHS%20providers,%C2%A33.5bn%20aggregate%20deficit. Accessed on 05 May 2025.

Williamson M, Sehjal R, Jones M, James C, Smith A. How critical cost analysis can save money in today's NHS: a review of carpal tunnel surgery in a district general hospital. BMJ Open Qual. 2018;7(2):e000115.

Mitchell WG, Kettwich SC, Sibbitt WL Jr, Sibbitt RR, Muruganandam M, Rolle NA, et al. Outcomes and cost-effectiveness of ultrasound-guided injection of the trochanteric bursa. Rheumatol Int. 2018;38(3):393-401.

Downloads

Published

2025-12-26

How to Cite

Baskar, S., Pattnaik, S., Khalid, M., Leo, S. J., Sidhu, G. A., & Gawad, M. (2025). Comparative analysis of landmark-guided intra-articular knee injections in outpatient clinics versus ultrasound-guided injections: a quality improvement study . International Journal of Research in Orthopaedics, 12(1), 18–23. https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20254201

Issue

Section

Original Research Articles