Proximal femoral nail versus dynamic hip screw in treatment of intertrochanteric fractures: a systematic review
DOI:
https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20253294Keywords:
Intertrochanteric fracture, Proximal femoral nail, Dynamic hip screw, Internal fixation, Orthopaedic trauma, Functional outcomeAbstract
Intertrochanteric femoral fractures are common in the elderly and typically require internal fixation. This systematic review compared the clinical and radiological outcomes of the proximal femoral nail (PFN) and the dynamic hip screw (DHS) by analyzing 25 studies published between 2000 and 2024 across PubMed, Scopus, Embase, Web of Science, and the Cochrane Library. Key parameters included operative time, intraoperative blood loss, complication and reoperation rates, union time, and functional outcomes measured by the Harris hip score (HHS). Pooled evidence showed that PFN offers significant advantages in unstable fractures (AO/OTA 31-A2 and A3), demonstrating shorter operative time, reduced blood loss, lower implant-failure and reoperation rates, faster radiological union, and higher HHS at 3- and 6-month follow-up compared with DHS. DHS produced comparable results in stable fracture patterns (AO/OTA 31-A1) but was associated with higher mechanical complications in complex cases. Although PFN requires greater technical expertise and carries a small risk of iatrogenic femoral shaft fracture, its intramedullary design provides biomechanical superiority that supports early mobilization and improved functional recovery, especially in elderly osteoporotic patients. Surgical decision-making should therefore consider fracture stability, patient comorbidities, and surgeon experience to optimize outcomes.
Metrics
References
Ching-Lung C, Seng BA, Manoj C, Eddie Siu-LC, Yoon-Sok C, Fen LH, et al. An updated hip fracture projection in Asia: The Asian Federation of Osteoporosis Societies study. Osteoporosis Sarcopenia. 2018;4(1):16-21. DOI: https://doi.org/10.1016/j.afos.2018.03.003
Gullberg B, Johnell O, Kanis JA. World-wide projections for hip fracture. 1997;7(5):407-13. DOI: https://doi.org/10.1007/PL00004148
Dennison EM, Harvey NC, Cooper C. Epidemiology of hip fracture: Worldwide geographic variation. Indian J Orthop. 2011;45(1):15-22. DOI: https://doi.org/10.4103/0019-5413.73656
Sharma A, Sethi A, Sharma S. Treatment of stable intertrochanteric fractures of the femur with proximal femoral nail versus dynamic hip screw: a comparative study. Rev Bras Ortop. 2018;53(4):477-81. DOI: https://doi.org/10.1016/j.rboe.2017.07.008
Brauer CA, Coca-Perraillon M, Cutler DM. Incidence and mortality of hip fractures in the United States. JAMA. 2009;302(14):1573-9. DOI: https://doi.org/10.1001/jama.2009.1462
Saudan M, Lubbeke A, Christophe S, Nicolas R, Richard S, Pierre H. Pertrochanteric fractures: Is there an advantage to an intramedullary nail? J Orthop Trauma. 2002;16(6):386-93. DOI: https://doi.org/10.1097/00005131-200207000-00004
Thusoo V, Nehru A, Sachin K, Arjun SC, Eshaan SS, Alok KV, et al. A comparative study of dynamic hip screws and proximal femoral nails in intertrochanteric fractures. Cureus. 2024;16(4):59063. DOI: https://doi.org/10.7759/cureus.59063
Figueras CG, Rio LTD, Laura GN, Jaume RB, Ramon HC. Traumatic hip dislocation in childhood. HIP Int. 2010;20(4):524-8. DOI: https://doi.org/10.1177/112070001002000417
Lil NA, Makwana VR, Patel TD, Patel AR. Comparative study of intertrochanteric fracture fixation using proximal femoral nail with and without distal interlocking screws. World J Orthoped. 2022;13(3):267-77. DOI: https://doi.org/10.5312/wjo.v13.i3.267
Aygün Ü, Şenocak E, Mehmet FA, Ali CÇ, Orkun H, Serdar T. An overview of patients with intertrochanteric femoral fractures treated with proximal femoral nail fixation using important criteria. BMC Musculoskeletal Disorders. 2024;25(1):1051. DOI: https://doi.org/10.1186/s12891-024-08197-0
Dai P, Zhou H, Xiaoyu M, Chang L, Zhiwei W, Yifan K. Proximal femoral nail anti‐rotation vs dynamic hip screws decrease the incidence of surgical site infections in patients with intertrochanteric fractures: A meta‐analysis. Int Wound J. 2023;20(8):3212-20. DOI: https://doi.org/10.1111/iwj.14200
Wang C, Duan N, Zhong L, Teng M, Kun Z, Qian W, et al. Biomechanical evaluation of a new intramedullary nail compared with proximal femoral nail antirotation and InterTAN for the management of femoral intertrochanteric fractures. Front Bioengineering. 2024;12:1353677. DOI: https://doi.org/10.3389/fbioe.2024.1353677
Tali MA, Ali et al. PFN versus DHS fixation in the management of intertrochanteric fractures. National J Clin Orthop. 2022;6(3):30-33. DOI: https://doi.org/10.33545/orthor.2022.v6.i3a.428
Zhang, Y., Li J, Imtiyaz HD, Layeeq AL. Does intramedullary nail have advantages over dynamic hip screw in the treatment of intertrochanteric fractures? A meta-analysis. BMC Musculoskeletal Disorders. 2023;24:67-10.
Shiraz, S., Shujauddin, et al.: Comparison of dynamic hip screw and proximal femoral nailing techniques in stable intertrochanteric fractures. Cureus. 2023;15:33366-10. DOI: https://doi.org/10.7759/cureus.33366
Zhang K, Zhang S, Jun Y, Weiqiang D, Shengnan W, Yirong C, et al. Proximal femoral nail vs. dynamic hip screw in treatment of intertrochanteric fractures: A meta-analysis. Med Sci Monitor. 2014;20:1628-33. DOI: https://doi.org/10.12659/MSM.890962
Kumar A, Ramesh DJ, Baibhav KA. A comparative study between DHS and PFN for the treatment of intertrochanteric fractures. Int J Orthopaed Sci. 2020;6(1):653-7. DOI: https://doi.org/10.22271/ortho.2020.v6.i1l.1938
Lone BA, Mushtaq S, Shahid S. Comparative study on evaluation of results of DHS versus PFN in intertrochanteric fractures. Int J Orthopaed Sci. 2024;10(1):84-8. DOI: https://doi.org/10.22271/ortho.2024.v10.i1b.3497
Kunwar OP. Assessment of functional outcome in intertrochanteric fractures between dynamic hip screw and proximal femoral nailing: A comparative study. Zenodo. 2023;3(12):38-42.
Yeo QY. Proximal femoral nail antirotation II versus dynamic hip screw in stable intertrochanteric femur fractures: A randomized controlled trial. Malay Orthop J. 2025;19(1):86-91. DOI: https://doi.org/10.5704/MOJ.2503.011
Kumar R, Singh RN, Singh BN. Comparative prospective study of proximal femoral nail and dynamic hip screw in treatment of intertrochanteric fracture femur. J Clin Orthop. 2012;3(1):23-8. DOI: https://doi.org/10.1016/j.jcot.2011.12.001
Singh S, Kumar M. Comparative study between proximal femoral nailing versus dynamic hip screw in intertrochanteric fractures. Int J Res Med Sci. 2023;9(11):845-50. DOI: https://doi.org/10.18203/2320-6012.ijrms20214067
Yuan X, Yao Q, Jie N, Libin P, Daxin Y. Proximal femoral nail antirotation versus dynamic hip screw for intertrochanteric fracture in elders: A meta-analysis. Zhonghua Yi Xue Za Zhi. 2014;94(11):836-9.
Sharma R. Comparative evaluation of proximal femoral nail anti-rotation versus dynamic hip screw for stable intertrochanteric femoral fractures: A meta-analysis of clinical outcomes. J Musculoskel Surg Res. 2022;6:123-30.
Muhammad S, Shafi ul H, Majid H, Muhammad Q. Functional outcomes of proximal femoral nail versus dynamic hip screw in intertrochanteric fractures. Professional Med J. 2024;31(10):567-72. DOI: https://doi.org/10.29309/TPMJ/2024.31.10.8276
Latheef MB, Sheth S, Basu A, Karnati AKR, Sadalagi P. Comparison of functional outcomes of pertrochanteric fractures of the femur managed with dynamic hip screw with a locking side plate versus proximal femoral nail. Int J Res Orthop. 2023;9(3):545-52. DOI: https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20231181
Shukla R, Pathak P, Arpit Cl. Comparative analysis of functional and radiological outcome of proximal femoral nail versus dynamic hip screw in treatment of intertrochanteric fractures. J Orthop Traumatol Rehabilit. 2022;14(1):24-31. DOI: https://doi.org/10.4103/jotr.jotr_73_21
Kumar R, Singh RN, Singh BN. Comparative study of functional outcome of the intertrochanteric fracture of femur managed by dynamic hip screw and proximal femoral nail. National J Clin Orthop. 2019;3(1):26-30. DOI: https://doi.org/10.33545/orthor.2019.v3.i1a.08
Kumar R, Sujai S, Sushant B, Abhinav B, Prajwal S, Hemanth, Latheef MB. Prevalence of intertrochanteric fractures of the femur and comparison of radiological outcomes when managed with proximal femoral nail vs. the dynamic hip screw with locking side plate in the Indian population. J Orthop. 2023;7(4):000251. DOI: https://doi.org/10.23880/jobd-16000251
Prakash AK, Nagakumar JS, Shanthappa AH, Venkataraman S, Kamath A. A Comparative Study of Functional Outcome Following Dynamic Hip Screw and Proximal Femoral Nailing for Intertrochanteric Fractures of the Femur. Cureus. 2022;14(4):e23803. DOI: https://doi.org/10.7759/cureus.23803