Hypovitaminosis D in adult patients scheduled for orthopaedic surgery: a cross-sectional and observational study

Authors

  • Gazala Abbas Department of Biochemistry, Shri Mata Vaishno Devi Institute of Medical Excellence, Katra, Jammu and Kashmir, India
  • Sparsh Dagoria Department of Orthopedics, All India Institute of Medical Sciences, Jammu, Jammu and Kashmir, India
  • Asma Yasin Dayanand Medical College, Ludhiana, Punjab, India
  • Tahir Afzal Department of Orthopaedics, Government Medical College and Hospital, Jammu, Jammu and Kashmir, India
  • Abdul M. Bhat Department of Orthopaedics, Government Medical College and Hospital, Jammu, Jammu and Kashmir, India
  • Nikhil Atri Department of Orthopaedics, Government Medical College and Hospital, Jammu, Jammu and Kashmir, India

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20260497

Keywords:

Hypovitaminosis D, Orthopaedic surgery, Vitamin D deficiency, Bone healing, BMI, Preoperative screening

Abstract

Background: Hypovitaminosis D is a common yet underdiagnosed nutritional deficiency with significant implications for orthopaedic surgical patients. Vitamin D plays a critical role in calcium homeostasis, bone metabolism, and muscle function—factors influencing bone healing, infection risk, and postoperative rehabilitation. Although global studies report high prevalence, limited Indian data exist for orthopaedic surgery patients.

Methods: A cross-sectional observational study was conducted in the Department of Orthopaedics, Government Medical College, Jammu, from September 2023 to February 2024. Fifty adult patients (>20 years) scheduled for elective orthopaedic surgery were included. Serum 25-hydroxyvitamin D (25(OH)D) levels were measured preoperatively using liquid chromatography–tandem mass spectrometry. Deficiency was defined as <20 ng/ml, insufficiency as 20–30 ng/ml, and optimal as >30 ng/ml. Demographic and clinical variables (age, sex, BMI) were recorded. Ethical clearance was obtained from the Institutional Ethics Committee (approval no. GMCJ/IEC/2023/241).

Results: Mean age was 56.17±15.23 years; 58% were male. Mean body mass index (BMI) was 25.61±4.21 kg/m², with 38% overweight. Vitamin D deficiency was present in 30% of patients, insufficiency in 40%, and optimal levels in 30%. Deficiency was more prevalent among males and overweight individuals, and highest in the 61–70-year age group (38%).

Conclusions: Hypovitaminosis D is highly prevalent among adults undergoing orthopaedic surgery. Overweight status and male gender were associated with higher risk. Routine preoperative screening and supplementation could improve surgical outcomes and reduce complications.

Metrics

Metrics Loading ...

References

Kaur J, Khare S, Sizar O, Givler A. Vitamin D Deficiency. 2025. In: StatPearls. Treasure Island (FL): StatPearls Publishing. 2025.

Holick MF. Vitamin D: Importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004;79(3):362-71. DOI: https://doi.org/10.1093/ajcn/79.3.362

DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr. 2004;80:1689S-96S. DOI: https://doi.org/10.1093/ajcn/80.6.1689S

Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium. Dietary Reference Intakes for Calcium and Vitamin D. Ross AC, Taylor CL, Yaktine AL, Del Valle HB, editors. Washington (DC): National Academies Press (US). 2011.

Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: An Endocrine Society guideline. J Clin Endocrinol Metab. 2011;96(7):1911-30. DOI: https://doi.org/10.1210/jc.2011-0385

Lips P. Worldwide status of vitamin D nutrition. J Steroid Biochem Mol Biol. 2010;121:297-300. DOI: https://doi.org/10.1016/j.jsbmb.2010.02.021

Marwaha RK, Tandon N, Garg MK, Kanwar R, Narang A, Sastry A, et al. Vitamin D status in healthy Indians aged 50 years and above. J Assoc Physicians India. 2011;59:706-9. DOI: https://doi.org/10.1007/s00198-010-1507-8

Binkley N, Novotny R, Krueger D, Kawahara T, Daida YG, Lensmeyer G, et al. Low vitamin D status despite abundant sun exposure. J Clin Endocrinol Metab. 2007;92(6):2130-5. DOI: https://doi.org/10.1210/jc.2006-2250

Bogunovic L, Kim AD, Beamer BS, Nguyen J, Lane JM. Hypovitaminosis D in patients scheduled to undergo orthopaedic surgery: a single-center analysis. J Bone Joint Surg Am. 2010;92(13):2300-4. DOI: https://doi.org/10.2106/JBJS.I.01231

Glowacki J, Hurwitz S, Thornhill TS, Kelly M, LeBoff MS. Osteoporosis and vitamin-D deficiency among postmenopausal women with osteoarthritis undergoing total hip arthroplasty. J Bone Joint Surg Am. 2003;85(12):2371-7. DOI: https://doi.org/10.2106/00004623-200312000-00015

Guardia G, Parikh N, Eskridge T, Phillips E, Divine G, Rao DS. Prevalence of vitamin D depletion among subjects seeking advice on osteoporosis: a five-year cross-sectional study with public health implications. Osteoporos Int. 2008;19(1):13-9. DOI: https://doi.org/10.1007/s00198-007-0456-3

Foo LH, Zhang Q, Zhu K, Ma G, Trube A, Greenfield H, et al. Relationship between vitamin D status, body composition and physical exercise of adolescent girls in Beijing. Osteoporos Int. 2009;20(3):417-25. DOI: https://doi.org/10.1007/s00198-008-0667-2

Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3):690-3. DOI: https://doi.org/10.1093/ajcn/72.3.690

Maier GS, Maus U, Lazovic D, Horas K, Roth KE, Kurth AA. Is there an association between low serum 25-OH-D levels and the length of hospital stay in orthopaedic patients after arthroplasty? J Orthop Traumatol. 2016;17(4):297-302. DOI: https://doi.org/10.1007/s10195-016-0414-y

Downloads

Published

2026-02-24

How to Cite

Abbas, G., Dagoria, S., Yasin, A., Afzal, T., Bhat, A. M., & Atri, N. (2026). Hypovitaminosis D in adult patients scheduled for orthopaedic surgery: a cross-sectional and observational study . International Journal of Research in Orthopaedics, 12(2), 356–358. https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20260497

Issue

Section

Original Research Articles