Total knee arthroplasty in pigmented villonodular synovitis: a case report and its management

Authors

  • Anand Kumar Department of Orthopedics, Government Medical College, Kota, Rajasthan, India
  • Sanjay Singh Rawat Department of Orthopedics, Government Medical College, Kota, Rajasthan, India
  • Ram Prasad Meena Department of Orthopedics, Government Medical College, Kota, Rajasthan, India
  • Ekaansh Karir Department of Orthopedics, Government Medical College, Kota, Rajasthan, India

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20243914

Keywords:

PVNS, TGCT, DPVNS, LPVNS

Abstract

Pigmented villonodular synovitis (PVNS) is a benign yet potentially aggressive proliferative lesion of the synovium, which can lead to significant morbidity, particularly when associated with osteoarthritis. This case report presents a 48-year-old male with a 2-year history of knee swelling and pain, exacerbated over the last 6 months, resulting in impaired daily activities. Clinical examination and imaging revealed severe osteoarthritis and soft tissue swelling around the knee. Surgical intervention involved total synovectomy and total knee arthroplasty, performed concurrently. The patient exhibited favorable postoperative outcomes, achieving full range of motion and resolution of symptoms. This case underscores the importance of recognizing PVNS as a contributor to knee osteoarthritis and highlights effective surgical management strategies to improve patient quality of life. Follow-up care is crucial to monitor for potential recurrence of the disease.

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References

Burton TM, Ye X, Parker ED, Bancroft T, Healey J. Burden of Illness Associated with Tenosynovial Giant Cell Tumors. Clin Ther. 2018 Apr;40(4):593-602.e1

Staals EL, Ferrari S, Donati DM, Palmerini E. Diffuse-type tenosynovial giant cell tumour: Current treatment concepts and future perspectives. Eur J Cancer. 2016 Aug;63:34-40]

West RB, Rubin BP, Miller MA, Subramanian S, Kaygusuz G, Montgomery K, Zhu S, Marinelli RJ, De Luca A, Downs-Kelly E, Goldblum JR, Corless CL, Brown PO, Gilks CB, Nielsen TO, Huntsman D, van de Rijn M. A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):690-5.

Rao AS, Vigorita VJ. Pigmented villonodular synovitis (giant-cell tumor of the tendon sheath and synovial membrane). A review of eighty-one cases. J Bone Joint Surg Am. 1984;66:76–94]

Flandry F, Hughston JC. Pigmented villonodular synovitis. J Bone Joint Surg Am. 1987;69:942–949

Ogilvie-Harris DJ, McLean J, Zarnett ME. Pigmented villonodular synovitis of the knee. The total arthroscopic synovectomy, partial arthroscopic synovectomy, and arthroscopic local excision. J Bone Joint Surg Am. 1992;74:119–23.

Beguin J, Locker B, Vielpeau C, Souquieres G. Pigmented villonodular synovitis of the knee:Results from 13 cases. Arthroscopy. 1989; 5:62–4.

Kim SJ, Shin SJ, Choi NH, Choo ET. Arthroscopic treatment for localized pigmented villonodular synovitis of the knee. Clin Orthop. 2000;379:224–30.

Brahmi M, Vinceneux A, Cassier PA. Current Systemic Treatment Options for Tenosynovial Giant Cell Tumor/Pigmented Villonodular Synovitis: Targeting the CSF1/CSF1R Axis. Curr Treat Options Oncol. 2016 Feb;17(2):10.

Zhao L, Zhou K, Hua Y, Li Y, Mu D. Multifocal pigmented villonodular synovitis in a child: A case report. Medicine (Baltimore). 2016 Aug;95(33):e4572.

Çevik HB, Kayahan S, Eceviz E, Gümüştaş SA. Tenosynovial giant cell tumor in the foot and ankle. Foot Ankle Surg. 2020 Aug;26(6):712-716.

Chang JS, Higgins JP, Kosy JD, Theodoropoulos J. Systematic Arthroscopic Treatment of Diffuse Pigmented Villonodular Synovitis in the Knee. Arthrosc Tech. 2017 Oct;6(5):e1547-e1551.

West RB, Rubin BP, Miller MA, Subramanian S, Kaygusuz G, Montgomery K, Zhu S, Marinelli RJ, De Luca A, Downs-Kelly E, Goldblum JR, Corless CL, Brown PO, Gilks CB, Nielsen TO, Huntsman D, van de Rijn M. A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):690-5.

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Published

2024-12-26

How to Cite

Kumar, A., Rawat, S. S., Meena, R. P., & Karir, E. (2024). Total knee arthroplasty in pigmented villonodular synovitis: a case report and its management . International Journal of Research in Orthopaedics, 11(1), 235–238. https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20243914