To evaluate the efficacy of platlet rich plasma injection in chronic lateral epicondylitis (tennis elbow)

Authors

  • Rahul Kadam Department of Orthopaedics, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Sachin Pandey Department of Orthopaedics, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Abhay Chhallani Department of Orthopaedics, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Santosh Pandhare Department of Orthopaedics, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Abhishek Gupta Department of Orthopaedics, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Ritesh Sawant Department of Orthopaedics, MGM Medical College, Navi Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20171466

Keywords:

Lateral epicondylitis, Tennis elbow, Platelet rich plasma

Abstract

Background: Platelet-rich plasma helps in repair because of its growth factor. Platelet-rich plasma has been used in humans for its healing properties. Increased concentration of growth factors and secretory proteins at may increase the process of healing on a cellular level. The PRP increases the incorporation of cells, proliferation, and differentiation in tissue regeneration of the cell involved.  This study was done to check the effectiveness of PRP injections in patients with chronic lateral epicondylitis or tennis elbow.

Methods: This study was done on the patients visiting the orthopaedic OPD at MGM medical college and hospital, kamothe, Navi Mumbai. Total number of patients for this study was 40 out of which 32 were male and 8 were females. The mean age of the patients was 48.1years (range 17-82 years).Study period was 3 months. Stastical tool used is visual analog score.

Results: Successful treatment was taken as more than 20% reduction i.e.(24 out of 40 patients)  in visual analog score after 3 month. The mean VAS score was decreased from 6.98 to 4.91 after 3 months in males. While in females, mean VAS score was decreased from 6.66 to 5.22 after 3 months of PRP injection in lateral epicondylitis.

Conclusions: Treatment of patients with PRP with chronic lateral epicondylitis or tennis elbow with PRP reduces pain and increases function of the affected elbow joint.

References

Silverstein B, Welp E, Nelson N, Kalat J. Claims incidence of work‐related disorders of the upper extremities: Washington State, 1987 through 1995. Am J Public Health. 1998;88(12):1827-33.

Walker-Bone K, Palmer KT, Reading I, Cooper C. Soft-tissue rheumatic disorders of the neck and upper limb: prevalence and risk factors. Semin Arthritis Rheum. 2003;33(3):185-203.

Henry M, Stutz C. A unified approach to radial tunnel syndrome and lateral tendinosis. Tech Hand Up Extrem Surg. 2006;10(4):200-5.

Anitua E, Sa´nchez M, Orive G (2010) Potential of endogenous regenerative technology for in situ regenerative medicine. Adv Drug Deliv Rev 15;62(7–8):741–752.

Everts PA, Brown Mahoney C, Hoffmann JJ. Platelet-rich plasma preparation using three devices: implications for platelet activation and platelet growth factor release. Growth Factors. 2006;24(3):165–71.

Mejia HA, Bradley JP. The effects of platelet-rich plasma on muscle, Basic Science and Clinical Application. 2011;19:149-53.

Pietrzak WS, Eppley BL. Platelet rich plasma: biology and new technology, Journal of Craniofacial Surgery. 2005;16(6):1043–54.

Marx RE. Platelet-rich plasma (PRP): What Is PRP and What Is Not PRP? Implant Dent. 2001;10:225–8.

Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med. 2006;34(11):1774–78.

Mishra A, Collado H, Fredericson M. Platelet-rich plasma compared with corticosteroid injection for chronic lateral elbow tendinosis. PMR. 2009;1(4):366–70.

Raeissadat SA, Rayegani SM, Hassanabadi H, Rahimi R, Sedighipour L, Rostami K. Is Platelet-rich plasma superior to whole blood in the management of chronic tennis elbow: one year randomized clinical trial. BMC Sports Sci Med Rehabil. 2014;18(6):12.

Malloy T, Wang Y, Murrell G. The roles of growth factors in tendon and ligament healing. Sports Med. 2003;33:381-94

G. Filardo, E. Kon, R. Buda, A. Timoncini, A. Di Martino, A. Cenacchi, et al.Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesionsKnee Surg Sports Traumatol Arthrosc. 2011;19:528–35.

D. Gould et al. Visual Analogue Scale (VAS). J Clin Nursing. 2001;10:697-706.

Altay T, Günal I, Oztürk H. Local injection treatment for lateral epicondylitis. Clin Orthop Relat Res. 2002;398:127–30.

Pruce AM, Miller JA Jr, Berger IR. Anatomic landmarks in joint paracentesis. Clin Symp. 1958;10(1):3–14.

Marx RE. Platelet-rich plasma (PRP): What Is PRP and What Is Not PRP? Implant Dent. 2001;10:225–8.

Carofino B, Chowaniec DM, McCarthy MB, Bradley JP, Delaronde S, Beitzel K, et al. Corticosteroids and local anesthetics decrease positive effects of platelet-rich plasma: an in vitro study on human tendon cells. 2012;28(5):711-9.

Creaney L, Wallace A, Curtis M, Conell D. Growth Factor-Based Therapies Provide Additional Benefit beyond Physical Therapy in Resistant Elbow Tendinopathy: A Prospective, Single Blind Randomized Trial of Autologous Blood Injections versus Platelet-Rich Plasma Injections. British J Sports Med. 2011;45:966-71.

Downloads

Published

2017-04-25

Issue

Section

Original Research Articles