A rare case of giant cell tumor in navicular bone: a case report
DOI:
https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20241973Keywords:
Giant cell tumor, Bone, Navicular boneAbstract
Giant cell tumor (GCT) is a benign but locally aggressive lesion of the bone. They are common in skeletally mature individuals with a slight female preponderance. Rare unusual presentations can occur. This case report describes a rare case of GCT of bone in the right navicular bone in a 25-year-old male patient who presented with complaints of pain and swelling in right foot and difficulty in walking. The diagnosis was made with radiological investigations and was then confirmed with histopathological evaluation. The lesion was managed with extensive curettage and bone grafting. Patient had complete resolution of symptoms post-surgery with no signs of local recurrence at 18-months follow-up.
References
McGrath PJ. Giant-cell tumor of bone: an analysis of 52 cases. J Bone Joint Surg. 1972;548:216-29.
Tomlinson, M, Kubicek, GJ, Ferreira, N, & Marais, LC. Case report: A typical presentation of giant cell tumour (GCT) of bone in the distal humerus of a child. SA Orthopaedic J. 2016;15(1):29-32.
Purohit S, Pardiwala DN. Imaging of giant cell tumor of bone. Indian J Orthop. 2007;41(2):91-6.
Balke M, Henrichs M, Gosheger G, Helmut A, Arne S, Michael K, et al. Giant cell tumors of the axial skeleton. Sarcoma. 2012;2012:410973.
Turcotte RE. Giant cell tumor of bone. Orthop Clin North Am. 2006;37(1):35-51.
Campanacci M, Baldini N, Boriani S, Sudanese A. Giant-cell tumor of bone. J Bone Joint Surg Am. 1987;69:106-14.
Oliveira VC, Van der Heijden L, Van der Geest, Campanacci DA, Gibbons CMH, Sande VD, et al. Giant cell tumours of the small bones of the hands and feet. Bone Joint J. 2013;95(6):838-45.
Puri A, Agarwal MG, Shah M, Jambhekar NA, Anchan C, Behle S. Giant cell tumor of bone in children and adolescents. J Pediatr Orthop. 2007;27(6):635-9.
Dahlin DC, Cupps RE, Johnson EW. Giant-cell tumor: a study of 195 cases. Cancer. 1970;25:1061-70.
Goldenberg RR, Campbell CJ, Bonfiglio M. Giantcell tumor of bone. J Bone Joint Surg. 1970;52A:619-64.
Biscaglia R, Bacchini P, Bertoni F. Giant cell tumor of the bones of the hand and foot. Cancer. 2000;88:2022-32.
Sobti A, Agrawal P, Agarwala S, Agarwal M. Giant Cell Tumor of Bone - An Overview. Arch Bone Jt Surg. 2016;4(1):2-9.
Muscolo DL, Ayerza MA, Aponte-Tinao LA. Giant cell tumours of bone. Curr Orthop. 2001;15:41-50.
Hasan O, Ali M, Mustafa M, Ali A, Umer M. Treatment and recurrence of giant cell tumors of bone A retrospective cohort from a developing country. Ann Med Surg (Lond). 2019;48:29-34..
Schutte HE, Taconis WK. Giant cell tumor in children and adolescents. Skeletal Radiol. 1993;22(3):173-6.
Pereira HM, Marchiori E, Severo A. Magnetic resonance imaging aspects of giant-cell tumours of bone. J Med Imaging Radiat Oncol. 2014;58(6):674-8.
Cavanna L, Biasini C, Monfredo M, Maniscalco P, Mori M. Giant cell tumor of bone. Oncologist. 2014;19(11):1207.
Balke M, Schremper L, Gebert C, Helmut A, Arne S, Gabriele K, et al. Giant cell tumor of bone: treatment and outcome of 214 cases. J Cancer Res Clin Oncol. 2008;134(9):969-78.
Becker WT, Dohle J, Bernd L, Ludger B, Arnim B, Miklos C, et al. Local recurrence of giant cell tumor of bone after intralesional treatment with and without adjuvant therapy. J Bone Joint Surg Am. 2008;90(5):1060-7.
Errani C, Ruggieri P, Asenzio MA, Angelo T, Simone C, Eugenio R, et al. Giant cell tumor of the extremity: a review of 349 cases from a single institution. Cancer Treat Rev. 2010;36(1):1-7.
Klenke FM, Wenger DE, Inwards CY, Rose PS, Sim FH. Giant cell tumor of bone: risk factors for recurrence. Clin Orthop Relat Res. 2011;469(2):591-9.
Kivioja AH, Blomqvist C, Hietaniemi K, Clement T, Anders W, Henrik CFB, et al. Cement is recommended in intralesional surgery of giant cell tumors: a Scandinavian Sarcoma Group study of 294 patients followed for a median time of 5 years. Acta Orthop. 2008;79(1):86-93.
Moon MS, Kim SS, Moon JL, Kim SS, Moon H. Treating giant cell tumours with curettage, electrocautery, burring, phenol irrigation, and cementation. J Orthop Surg. 2013;21(2):209-12.
Lim YW, Tan MH. Treatment of benign giant cell tumours of bone in Singapore. Ann Acad Med Singapore. 2005;34(3): 235-37.
Khan M. Metastatic Navicular Giant Cell Tumour (Osteoclastoma)- A Case Report With 16 Year Follow-Up. J Orthop. 2007;41(2):154-7.
Zacharia B, Pai PK, Paul M. Clinical and Radiological Profile of Ten Interesting Though Rare Presentations of Giant Cell Tumor of Bone. Indian J Surgical Oncol. 2020;11(3):527-37.
