The outcome of fresh frozen allografts in bone healing: a prospective study, in a tertiary care centre, India

Authors

  • Raghu Yelavarthi Department of Orthopaedics, Apollo Hospitals, Visakhapatnam, Andhra Pradesh, India http://orcid.org/0000-0002-6111-869X
  • Jairamchander Pingle Department of Orthopaedics, Apollo Hospitals Jubilee hills, Hyderabad, Telangana, India
  • Sadhan Palakuri Department of Orthopaedics, Apollo Hospitals Jubilee hills, Hyderabad, Telangana, India

DOI:

https://doi.org/10.18203/issn.2455-4510.IntJResOrthop20220612

Keywords:

Fresh frozen allografts, Bone healing, Outcome, Prospective study

Abstract

Background: Massive bone loss is a major problem in modern orthopaedics. Allograft use in clinical practice has become a desirable option. Allografts are used to reconstruct bony defects in different disorders in orthopaedic surgeries. Fresh frozen allograft is a reconstructive biologic option for osseous defects. This article evaluates the outcome of fresh frozen allografts in bone healing in different orthopaedic procedures.

Methods: Prospective non-randomized trial was conducted in 136 patients of any age presenting to orthopaedic OPD with bone defects/disorders requiring bone grafting in a tertiary care centre. Ann et al radiological criteria for new bone formation, was used for grading outcome.

Results: The age of the patients varied between 12-76 years. About 8.1% patients belonged to 10-25 years age group, 39% to 26-40 years, 25% to 41-50 years, 15.4% to 51-60 years, 6.6% to 61-70 years and 5.9% to above 70 years age group. Mean age was 39.7 years. There were 61% male and 39% female patients. Minimum follow-up period was 1 month and maximum 4 years. Allografting was performed for 46 fractures with bone loss, 33 fractures with non-union/delayed union, 25 arthroplasties, 13 arthrodeses and 19 tumours. Follow-up results at two months showed that 84.6% had good, 12.5% had fair and 2.9% had bad results.

Conclusions: Allografting is one of the best options available for bone defects, especially in younger patients with a high life expectancy because of its potential durability.

Author Biographies

Raghu Yelavarthi, Department of Orthopaedics, Apollo Hospitals, Visakhapatnam, Andhra Pradesh, India

Consultant, Department of Orthopaedics

Jairamchander Pingle, Department of Orthopaedics, Apollo Hospitals Jubilee hills, Hyderabad, Telangana, India

Senior Consultant, Department of Orthopaedics

Sadhan Palakuri, Department of Orthopaedics, Apollo Hospitals Jubilee hills, Hyderabad, Telangana, India

Consultant, Department of Orthopaedics

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Published

2022-02-25

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Original Research Articles