Monostotic fibrous dysplasia of fibula: a rare case report


  • Bhupes Sil Department of Orthopedics, Agartala Government Medical College, Agartala, Tripura, India
  • Naveen V. Department of Orthopedics, Agartala Government Medical College, Agartala, Tripura, India
  • Dipen Roy Department of Orthopedics, Agartala Government Medical College, Agartala, Tripura, India



Fibrous dysplasia, Ground-glass, Radiographic examination


Fibrous dysplasia is a developmental anomaly of bone formation that may exist in monostotic or polyostotic form. Monostotic fibrous dysplasia of fibula is a rare case with unusual site and most common sites being facial bones, ribs, proximal femur and tibia. We report a case of 10-year-old boy attended our hospital with occasional pain in left leg while having strenuous activity. On clinical examination there was no obvious swelling with normal appearing skin. Radiographic examination revealed lesion with both radiopaque and radiolucent features showing a “ground-glass” appearing lesion in proximal one third of fibula. Differential diagnosis considered are simple bone cyst, non-ossifying fibroma, osteo-fibrous dysplasia, adamantinoma. As a definitive treatment curettage was done and biopsy sent for histopathological examination, which confirmed he diagnosis. Follow up after 10 months shows normal bone growth as evidenced radiologically and patient is asymptomatic. Case in detail and recent review of literature has been discussed. From our case, we have shown that it is possible to treat uncomplicated fibrous dysplasia with minimally invasive approach of simple curettage. Patient is symptomatically relieved within 2 months without any complications.


Dicaprio MR, Enneking WF. Fibrous dysplasia. Patho physiology, evaluation, and treatment. J Bone Joint Surg Am. 2005;87:1848-64.

MacDonald-Jankowski D. Fibrous dysplasia: A systematic review. Dentomaxillofac Radiol. 2009;38:196-215.

Campanacci M. Bone and soft tissue tumors: clinical features, imaging, pathology and treatment. New York: Springer science and Business Media. 1990.

De Melo WM, Sonora CK, Hochuli-Vieira E. Monostotic fibrous dysplasia of the mandible. Craniofac Surg. 2012;23:e454.

Nishita Y, Tsukushi S, Hosono K, Nakashima H, Yamaha Y, Urakawa H et al. Surgical treatment for fibrous dysplasia of femoral neck with mild but prolonged symptoms: a case series. J Orthop Surg Res. 2015;110:63.

Enneking WF, Rathe R, Cornwall G. Clinical musculoskeletal pathology. Office of Medical Informatics at the university of Florida. 1998.

Menon S, Venkatswamy S, Ramu V, Banu K, Sham E, Kashyap VM. Craniofacial dysplasia: literature review. Ann Maxillofac Surg. 2013;3:66-71.

Boyce AM, Brillante MBHA, Kushner H, Wientroub S, Riminucci M, Bianca P, et al. A randomized, double blind, placebo-controlled trail of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 2014;99(11):4133-40.

Tong Z, Zhang W, Jiao N, Wang K, Chen BO, Yang T. Surgical treatment of fibrous dysplasia in proximal femur. Exp Ther Med. 2013;5(5):1355-8.






Case Reports