To study the efficacy of Rhus tox in management of cases of osteoarthritis of knee joint
Keywords:Arthritis, Rheumatism, Osteoarthritis, Osteophytes, NSAID’s., WOMAC, Kellgren and Lawrence System
Background: Arthritis and rheumatism are among the commonest forms of chronic disease and, with an aging population, are set to become commoner still. Strictly speaking, arthritis means disease of the joints, while rheumatism is disease of the soft connective tissues which support and move the joints. There are many problems with current conventional treatment of arthritis and rheumatism. Although the new generation of NSAIDs is safer, they are only glorified painkillers, which do not affect the basic disease process. Similarly for rheumatoid arthritis, a range of powerful drugs is available but all of these have long and alarming lists of side effects. Thus the main aim of this research study is to prove the efficacy of Homoeopathy in managing cases of Osteoarthritis without any side-effects.
Methods: 30 cases were selected fitting the case definition. Age group of 45-79 years was chosen for the study. Inclusion and exclusion criteria were laid down. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Kellgren and Lawrence system of classifying the severity of knee-osteoarthritis were used to assess the severity and outcome.
Results: All the results were tabulated. Graphical presentation was made of all the observations. Scores before and after treatment was compared. It was found that there was vast difference in scores before and after treatment.
Conclusions: Rhus tox was found to be effective in managing cases of Osteoarthritis of Knee Joint.
Lane NE, Brandt K, Hawker G, Peeva E, Schreyer E, Tsuji W, et al. OARSI-FDA initiative: defining the disease state of osteoarthritis. Osteoarthr Cartilage. 2011;19(5):478-82.
Litwic A, Edwards MH, Dennison EM, Cooper C. Epidemiology and burden of osteoarthritis. Br Med Bull. 2013;105:185-99.
Lohmander LS, Brandt KD, Mazzuca SA, Katz BP, Larsson S, Struglics A, et al. Use of the Plasma Stromelysin (Matrix Metalloproteinase 3) Concentration to Predict Joint Space Narrowing in Knee Osteoarthritis. Arthritis Rheum. 2005;52(10):3160-7.
Lohmander LS, Ionescu M, Jugessur H, Poole AR. Changes in joint cartilage aggrecan after knee injury and in osteoarthritis. Arthritis Rheum. 1999;42(3):534-44.
Dieppe PA, Lohmander LS. Pathogenesis and management of pain in osteoarthritis. Lancet. 2005;365(9463):965-73.
Hunter DJ, Felson DT. Osteoarthritis. BMJ. 2006;332(7542):639-42.
Hunter DJ, Guermazi A, Roemer F, Zhang Y, Neogi T. Structural correlates of pain in joints with osteoarthritis. Osteoarthr Cartilage. 2013;21(9):1170-8.
Hayashi D, Guermazi A, Kwoh CK. Clinical and Translational Potential of MRI Evaluation in Knee Osteoarthritis. Curr Rheumatol Rep. 2014;16(1):1-9.
Felson DT, Lawrence RC, Dieppe PA, Hirsh R, Helmick CG, Jordoan JM, et al. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med. 2000;133(8):635–46.
Felson DT, Niu J, Clancy M, Sack B, Alibadi P, Zhnag Y. Effect of Recreational Physical Activities on the Development of Knee Osteoarthritis in Older Adults of Different Weights: The Framingham Study. Arthritis Rheum. 2007;57(1):6–12.
Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman B, Aliabadi P, Levy D. Risk factors for incident radiographic knee osteoarthritis in the elderly. Arthritis Rheum. 1997;40(4):728-33.
Ezzo J, Hadhazy V, Birch S, Lao L, Kaplan G, Hochberg M, et al. Acupuncture for osteoarthritis of the knee: a systematic review. Arthritis Rheum. 2001;44(4):819-25.
R Altman, E Asch, D Bloch, G Bole, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis & Rheumatol. 1986;8:1039-49.
Brandt KD, Dieppe P, Radin EL. Etiopathogenesis of osteoarthritis. Rheum Dis Clin North Am. 2008;34(3):531-59.
Torres L, Dunlop DD, Peterfy C, Guermazi A, Prasad P, Hayes KW, et al. The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis. Osteoarthritis Cartilage. 2006;14(10):1033-40.
Hartz AJ, Fischer ME, Bril G, Kelber S, Rupley D, Oken B, et al. The association of obesity with joint pain and osteoarthritis. J Chronic Dis. 1986;39(4):311-9.
Arthritis Impact Measurement Scales (AIMS/AIMS2). Available at www.rheumatology. org/.../Western-Ontario-McMaster-Universities-Osteoarthritis. Accessed on 01 November 2016.
Kellgren and Lawrence system for classification of osteoarthritis of knee. Available at https://radiopaedia.org/.../kellgren-and-lawrence-system-for-classification-of-osteoarthritis. Accessed on 04 November 2016.
Jonas WB, Linde K, Ramirez G. Homeopathy and rheumatic disease. Rheumatic disease clin North Am. 2000;26(1):117–23.
Soeken KL. Selected CAM therapies for arthritis-related pain: the evidence from systematic reviews. Clin J Pain. 2004;20(1):13–8.
Bell IR, Lewis DA, Brooks AJ, Shwartz GE, Lewis SE, Walsh BT, et al. Improved clinical status in fibromyalgia participants treated with individualized homeopathic remedies versus placebo. Rheumatol (Oxford). 2004;43(5):577–82.
Long L, Ernst E. Homeopathic remedies for the treatment of osteoarthritis: a systematic review. British Homeopathic J. 2001;90(1):37–43.