A case report on the effect of Cissus quadrangularis on fracture union in 26 years aged man


  • Naveen Kumar L. Department of Orthopaedics,Brindhavvan Areion Hospital, Bangalore, Karnataka
  • Dharitri Joshi V.I.P.S., Bangalore, Karnataka,




Cissus quadrangularis Linn., Bennett’s fracture, Fracture union


Ayurveda the ancient science of medicine describes various herb preparations that achieve the hastening of bone healing. Cissus quadrangularis Linn. is an indigenous medicinal plant which belongs to a family of Vitaceae. A case study was undertaken to evaluate the fracture union and effectiveness in reduction of pain and swelling in a 26 year old male with Bennett’s fracture. A quick union of fracture was observed within 6 weeks of treatment with C. quadrangularis. Post treatment radiographic reports showed united fracture with good amount of callus.


Brahmkshatriya HR, Shah KA, Ananthkumar GB, Brahmkshatriya MH. Clinical evaluation of Cissus quadrangularis as osteogenic agent in maxillofacial fracture: A pilot study. Int Quarterly J Res Ayurveda. 2015;36(2):169-73.

Muthusami S, Senthilkumar K, Vignesh C, Ilangovan R, Stanley J, Selvamurugan N, et al. Effects of Cissus quadrangularis on the proliferation, differenti¬ation and matrix mineralization of human osteoblast like SaOS-2 cells. J Cell Biochem. 2011;112(4):1035-45.

Arvind R, Changam SS, Vimal KR. A Case Report on the Effect of Cissus quandranglis on Bone Healing in 80yrs Aged Woman. J Complement Med Alt Healthcare. 2018;5(3):555663.

Singh V, Singh N, Pal US, Dhasmana S, Mohammad S, Singh N. Clinical evaluation of Cissus quadrangularis and moringa oleifera and osteoseal as osteogenic agents in mandibular fracture. National J Maxillofacial Surg. 2011;2(2):132-6.

Managutti AM, Shah DN, Patel JC, Puttanikar NY, Shah DS, Mangutti SA. Evaluation of Clinical Efficacy of Cissus quadrangularis in Pain Management and Bone Healing after Implant Placement: A Pilot study. Int J Oral Implantol Clin Res. 2015;6(2):35-9.

Mishra G, Srivastava S, Nagori BP. Pharmacological and therapeutic activity of Cissus quadrangularis: An overview. Int J PharmTech Res. 2010;2(2):1298-310.

Research Guidlines for Evaluating the safety and Efficacy of Herbal Medicines, World Health Organization, Regional Office for the Western Pacific, Geneva, Switzerland; 1993.