Published: 2019-06-27

Multiple extradigital glomus tumors of the ankle and foot with limb hypoplasia in a child: a case report

Chiao Yee Lim, Sijie Ng, Suryasmi Duski, Ping Ching Chye


Glomus tumors are rare tumors, and mostly occur in the fingertips and/ or subungual location. Multiple extradigital glomus tumors are extremely rare. We hereby described a rare case of multiple extradigital glomus tumor of the ankle and foot in a 11 year old girl with hypoplasia of the affected limb. The patient presented with swellings over her right ankle and foot for the past 5 years. The swellings were initially painless but became painful for the past 15 months. On examination, patient’s right leg and foot appeared to be smaller when compared to the left side. There were multiple vague swellings over the dorsum of right food and lateral aspect of right ankle, which were very tender to touch. There was no overlying skin changes observed. Magnetic resonance imaging showed multiple well defined, encapsulated lesions of varying sizes at the level of distal third right fibula and foot. The lesions appeared isointense to muscle in T1-weighted image, hyperintense in T2-weighted image with enhancement post-contrast. Excision biopsy of the right lateral distal leg swelling was performed. Histopathological examination of the excised mass confirmed the diagnosis of glomus tumor. In view of her parents were not keen for any further surgical intervention, the patient will be evaluated regularly, and any enlarging painful lesions will be excised as required. The clinical diagnosis of multiple extradigital glomus tumors is much more problematic due to its rarity. The physicians must be aware of this differential diagnosis so that early diagnosis and treatment could be administered to the patients.


Glomus tumor, Extradigital glomus tumor, Multiple glomus tumors

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Schiefer TK, Parker WL, Anakwenze OA, Amadio PC, Inwards CY, Spinner RJ. Extradigital glomus tumors: A 20-year experience. Mayo Clin Proc. 2006;81(10):1337-44.

Baek HJ, Lee SJ, Cho KH, Choo HJ, Lee SM, Lee YH, et al. Subungual Tumors: Clinicopathologic Correlation with US and MR Imaging Findings. Radiographics. 2010;30(6):1621-36.

Balaram AK, Hsu AR, Rapp TB, Mehta V, Bindra RR. Large solitary glomus tumor of the wrist involving the radial artery. Am J Orthop (Belle Mead NJ). 2014;43(12):567-70.

Maxwell GP, Curtis RM, Wilgis EF. Multiple digital glomus tumors. J Hand Surg Am. 1979;4(4):363-7.

Haiyat S, Akhtar K, Alam F, Siddiqui A. Extradigital Glomus Tumour of Ankle in a Toddler: A Rare Case Report with Unusual Presentation. J Med Surg Pathol. 2018;03(02):3-5.

Goodman TF. Multiple Glomus Tumors. Arch Dermatol. 1971;103(1):11.

Iliescu OA, Benea V, Georgescu SR, Rusu A, Manolache L. Multiple glomus tumors. J Dermatol Case Rep. 2008;2(2):24-7.

Goldblum JR, Weiss SW, Folpe AL. Perivascular tumors. Enzinger and Weiss’s Soft Tissue Tumors. Chapter 25. 6th ed. Elsevier Health Sciences; 2013: 747-763.

Anakwenze OA, Parker WL, Schiefer TK, Inwards CY, Spinner RJ, Amadio PC. Clinical features of multiple glomus tumors. Dermatologic Surg. 2008;34(7):884-90.

Friske JE, Sharma V, Kolpin SA, Webber NP. Extradigital glomus tumor: a rare etiology for wrist soft tissue mass. Radiol Case Reports. 2016;11(3):195-200.