DOI: http://dx.doi.org/10.18203/issn.2455-4510.IntJResOrthop20183685

Study of effects of negative pressure wound therapy in contaminated wounds

Atin Kundu, Satyendra Phuljhele, Nitin Wale, Harjot Singh Gurudatta, Vimal Agrawal

Abstract


Background: Negative pressure wound therapy is an advanced wound therapy technique that helps in healing the wounds and accelerates granulation tissue as well as wound closure.

Methods: Prospective randomized interventional study was done in Dept. of Orthopedics, Dr. BRAM Hospital, Pt. JNM Medical college, Raipur during period from January 2016 to December 2016 involving 25 patients with open fractures up to Gustilo Anderson grade IIIB. All were subjected to this wound technique and response was observed as granulation, size of wound and closure duration.

Results: There was up to 10 to 20 mm reduction in wound size with each dressing in half the patients and up to 10 mm in other half of the patients. There was significant reduction in the bacterial growth in all patients and closure was attained in all the subjects after a few therapies.

Conclusions: Negative pressure wound therapy is a promising technique to reduce the size of the wound in large wound associated with compound fractures and hasten the healing of wound and its closure.


Keywords


Vacuum assisted closure, Negative pressure wound therapy, NPWT, Closure, Dressing

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References


Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacuum assisted closure; a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1998;38:553-62.

Caudle RJ, Stern PJ. Severe open fractures of the tibia. J Bone Joint Surg Am. 1987;69(6):801-7.

Banwell PE, Teotl L. Topical negative pressure (TNP):The evolution of a novel wound therapy. J Wound Care. 2003;12(1):28-30.

Gustilo RB, Mendoza RM. Problems in the management of type 3 open fractures. J Trauma. 1984;24:742-6.

Morykwas MJ, Argenta LC. Vacuum-assisted closure:a new method for wound control and treatment: clinical experience. Ann Plastic Surg. 1997;38:563–77.

Hunt TK. The physiology of wound healing. Ann Emergency Med. 1988;17(12):1265–73.

Mehbod AA, Ogilvie JJ, Pinto MR, Schwender JD, Transfeldt EE, Wood KB, et al. Postoperative deep wound infections in adults after spinal fusion:Management with Vacuum-Assisted Wound Closure. J Spinal Disord Tech. 2005;18:14-7.

Mooney JF, Argenta LC, Marks MW, Morykwas MJ, deFranzo AJ. Treatment of soft tissue defects in pediatric patients using the V.A.C. system. Clin Orthop Rel Res. 2000;376:26-31.

Philbeck TE, Whittington KT, Millsap MH, Briones RB, Wight DG, Schroeder WJ. The clinical and cost effectiveness of externally applied negative pressure wound therapy in the treatment of wounds in home healthcare Medicare patients. Ostomy Wound Manage. 1999;45(11):41-50.

Argenta LC, Morykwas MJ. Vacuum assisted closure:a new method for wound control and treatment:clinical experience. Ann Plast Surg. 1997;38(6):563-76.

Sinha K, Chauhan VD, Maheshwari R. Vacuum Assisted Closure Therapy versus Standard Wound therapy for Open Musculoskeletal Injuries. Adv Orthop. 2013;245940.

Ford CN, Reinhard ER, Yeh D, Syrek D, De Las Morenas A, Bergman SB, et al. Interim analysis of a prospective, randomized trial of vacuum-assisted closure versus the health point system in the management of pressure ulcers. Ann Plast Surg. 2002;49(1):55-61

Müllner T, Mrkonjic L, Kwasny O, Vécsei V. The use of negative pressure to promote the healing of tissue defects:a clinical trial using the vacuum sealing technique. Br J Plast Surg. 1997;50:194–9.

Ilizarov GA. The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop Relat Res. 1989;238:249-81.

Moss SE, Klein R, Klein BE. Prevalence and incidence of lower extremity amputation in diabetic foot. Arch Intern Med. 1992;152(3):610-6.